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单边或面部裂中的偏见:一个系统的范围审查
Matthew Fell1,2, Daniel Bradley3, Ambika Chadha4,5
1Spires Cleft Centre, John Radcliffe Hospital, Oxford, UK.
概括
对单边口唇裂 (UCLP) 侧面性的研究揭示了左侧偏好. 虽然关于裂侧的原因和结果的发现正在出现,但需要更多的研究来区分影响.
科学领域:
- 面研究的研究.
- 发育生物学是发展生物学.
- 遗传学和公共卫生
背景情况:
- 带有或没有裂口的单侧裂口唇 (UCLP) 呈现方向不对称.
- 了解这种不对称的原因和影响对于有针对性的干预至关重要.
研究的目的:
- 系统地审查关于UCLP偏见的文献.
- 绘制有关与左侧与右侧UCLP相关的原因和结果的当前知识.
主要方法:
- 使用Medline和Embase数据库的系统搜索进行范围审查.
- 包括从开始到2023年5月的研究,重点研究患有UCLP的人类.
主要成果:
- 40项研究证实左侧偏好UCLP.
- 裂侧面性与牙异常和手性等表型一起发生.
- 研究了潜在的原因 (染色体,遗传,环境) 和结果 (面部特征,生长,心理特征),一些证据表明右侧UCLP的结果更差.
结论:
- 研究UCLP偏见是一个不断扩大的领域,早期有前途的发现.
- 研究表明,基于裂横向性的原因和结果可能存在差异.
- 需要进一步调查,以充分阐明UCLP偏见的含义.
关键词:
嘴唇裂口是一个问题.嘴唇裂和 palatal palatal 裂是指口唇裂和 palatal 裂是指口唇裂和 palatal 裂是指口唇裂.病因 病因学 病因学遗传学 遗传学 遗传学 是一个结果就是结果.更多相关视频
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