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Updated: Jul 8, 2025

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
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Published on: December 30, 2016

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хлорпромазин 通过干扰 pyruvate kinase M2 干扰质母细胞瘤的生物能效而影响质母细胞瘤

Claudia Abbruzzese1, Silvia Matteoni1, Paola Matarrese2

  • 1Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy.

Cell death & disease
|December 13, 2023
PubMed
概括

хлорпромазин (CPZ) 通过向糖分分解酶PKM2.2,显示出治疗质母细胞瘤 (GBM) 的前景. 这种神经乱药物抑制了GBM细胞中的华堡效应,提供了潜在的新疗法策略.

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