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Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
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一个由染色质调节的双相电路协调IL-1β介导的炎症

Ezio T Fok1,2,3, Simone J C F M Moorlag4, Yutaka Negishi1,2

  • 1Department of Cell Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, the Netherlands.

Nature genetics
|December 13, 2023
PubMed
概括

一种新的长非编码RNA,AMANZI,通过控制INTERLEUKIN-1β (IL-1β) 和INTERLEUKIN-37 (IL-37) 的表达来调节炎症. 这一发现揭示了一种基于色素的机制,它协调了相反的炎症状态.

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