在实验室中生产只限于猫的Toxoplasma前性阶段

Ana Vera Antunes1, Martina Shahinas1, Christopher Swale1

  • 1Institute for Advanced Biosciences (IAB), Team Host-Pathogen Interactions and Immunity to Infection, INSERM U1209, CNRS UMR5309, University Grenoble Alpes, Grenoble, France.

Nature
|December 13, 2023
PubMed
概括

两种转录因子,AP2XII-1和AP2XI-2,通过在太基因阶段沉默,控制Toxoplasma gondii的性繁殖. 它们的消耗使得体外甲虫的发展成为可能,从而绕过了对猫的需求.