患有慢性脏疾病的住院患者和临床药剂师干预的住院患者中与药物相关的问题
Su Zhang1, Guo-Bing Zhang1, Ping Huang1
1Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
BMC geriatrics
|December 13, 2023
概括
与药物相关的问题 (DRPs) 常见于患有慢性病 (CKD) 的住院患者. 临床药剂师的干预显著减少了DRP,突出了它们在患者安全和治疗疗效方面的关键作用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床药房 临床药房
- 药物经济学 药物经济学
背景情况:
- 患有慢性病 (CKD) 的患者因复杂的并发症和改变的药理动力学而面临药物相关问题 (DRP) 的风险增加.
- 住院的CKD患者经常经历多次DRP,影响治疗的安全性和有效性.
研究的目的:
- 在住院CKD患者中识别DRPs及其促成因素.
- 评估临床药剂师服务在检测和干预DRPs方面的有效性.
主要方法:
- 对中国江省914名住院慢性病患者的前性研究.
- 使用欧洲制药护理网络 (PCNE) 系统分类的DRP.
- 使用SPSS版本 26.0.0 的统计分析.
主要成果:
- 45.95%的患者在干预之前经历了463次DRP,平均为每位患者0.51.
- 治疗的安全性 (43.84%) 和疗效 (43.20%) 是主要的DRP类别.
- 药物选择问题 (60.26%) 是最常见的,特别是抗生素和心血管药物.
- 临床药剂师的干预导致了85.53%的推接受率和84.23%的DRP解决率.
- 干预后,DRP患病率降至7.77%,平均为每名患者0.08个DRP.
结论:
- 在中国的住院CKD患者中,DRP普遍存在.
- 慢性脏病第四阶段,并发病,多药和长时间住院是DRP的关键风险因素.
- 临床药剂师显著改善了DRP检测和解决方案,提高了科病房的患者护理.
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