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表达ASC的pyroptotic细胞外囊泡通过保护B细胞来缓解败血症

Weiying Huang1, Ben Wang1, Qianmin Ou1

  • 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, South China Center of Craniofacial Stem Cell Research, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China.

Molecular therapy : the journal of the American Society of Gene Therapy
|December 14, 2023
PubMed
概括

鉴定和特征化了热性细胞外囊泡 (pyroEVs). 这些pyroEVs保护B细胞并通过抑制Toll-like受体4来改善败血症的生存率.

关键词:
B 细胞 B 细胞与亡相关的含有CARD的斑状蛋白质.介质细胞干细胞介质细胞干细胞热致灭 (pyroptosis) 是一种致的过程.皮罗普托特细胞外囊泡.这是一种血症.

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