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对患有自身免疫性甲状腺炎的青少年女孩的精神病学分析
Engin Aydin1, Dilek Bingöl Aydin2, Gresa Çarkaxhiu Bulut3
1Pediatrics, Health Sciences University Zeynep Kamil Women and Children Diseases Training and Research Hospital, İstanbul, TUR.
Cureus
|December 14, 2023
概括
患有哈西莫托甲状腺炎 (HT) 的乙甲状腺女孩表现出增加的焦虑和精神病理. 甲状腺自身免疫,即使没有甲状腺功能障碍,也与情绪障碍有关,抗TPO抗体是抑郁症的重要危险因素.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 免疫学 免疫学 免疫学
背景情况:
- 甲状腺自身抗体与精神疾病有关,独立于甲状腺功能.
- 橋本氏甲状腺炎 (HT) 是一种自身免疫性甲状腺疾病,其特征是甲状腺自身抗体.
研究的目的:
- 为了研究甲状腺自身免疫和情绪障碍之间的关联,在带有哈西莫托甲状腺炎 (HT) 的乙甲状腺女孩中.
主要方法:
- 一项涉及82名青春期女孩 (41名HT,41名对照) 的病例控制研究.
- 基于抗TPO/抗Tg抗体和甲状腺超声波来诊断HT.
- 精神病学评估包括儿童抑郁症清单 (CDI),儿童焦虑相关情绪障碍屏幕 (SCARED) 和K-SADS-PL面试.
主要成果:
- 患有HT的患者的SCARED分数显著更高,特别是分离和社会焦虑.
- 在HT组中,精神病学诊断明显高于HT组 (66%与19.5%相比).
- 抑郁症,通用焦虑症和社会恐惧症的发病率在HT组中较高. 抗TPO水平是抑郁症障碍的重要危险因素.
结论:
- 患有哈西莫托甲状腺炎的甲状腺小女孩表现出显著的心理测量障碍.
- 自免疫性甲状腺疾病与精神疾病有关,即使没有明显的甲状腺功能障碍.
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