美国老年人多波阿片类药物使用的预测因素
Gillian Fennell1, Mireille Jacobson1,2, Hanna Grol-Prokopczyk3
1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.
Innovation in aging
|December 14, 2023
概括
在老年人中,长期阿片类药物治疗 (L-TOT) 的预测是年轻的年龄,较低的财富,特定的美国地区,疼痛类型和频繁的医生访问. 这些因素突出了慢性疼痛管理中干预和研究的关键领域.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 长期阿片类药物治疗 (L-TOT) 在患有慢性疼痛的老年人中很普遍,尽管其止痛效果有限.
- 老化代谢增加了与长期使用阿片类药物相关的风险,包括伤害和过量服用.
- 老年人L-TOT的预测因子没有得到充分的记录,需要进一步的研究.
研究的目的:
- 确定老年人L-TOT的人口,社会经济,地理和健康相关预测因素.
- 分析与单波和多波阿片类药物使用相关的因素.
主要方法:
- 利用了来自51岁及以上年龄组的健康与退休研究 (N=10,713) 的5个数据波.
- 使用多项逻辑回归来预测阿片类药物使用模式 (不使用,单波,多波).
- 在预测模型中包括人口,社会经济,地理,健康和医疗保健因素.
主要成果:
- 年龄较小,家庭财富较低,居住在美国中西部,南部或西部地区,经历干扰性疼痛,背痛或关节炎疼痛,以及频繁的医生访问预测了单波和多波阿片类药物使用.
- 多波用户不太可能是黑人,西班牙裔或从未结婚的人.
- 相对风险比率 (RRR) 显示了这些预测因素的显著关联.
结论:
- 人口,社会经济,地理和医疗保健因素预测了老年人长期多年使用阿片类药物的情况.
- 地理区域和医生访问的频率是政策和研究关注的关键领域.
- 研究结果为老龄化人口中的L-TOT预测因子提供了新的见解.
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