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Updated: Jul 8, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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通过序列分析和AlphaFold2-预测模型,识别了对人类G6PC2功能至关重要的结构动图

Emily M Hawes1, Derek P Claxton1, James K Oeser1

  • 1Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, U.S.A.

Bioscience reports
|December 14, 2023
PubMed
概括

研究人员研究了G6PC2蛋白质,该蛋白质对于调节禁食血糖 (FBG) 至关重要. 他们发现特定的结构特征和共同的遗传变异影响其活性,可能引导开发新的FBG降低药物.

关键词:
葡萄糖的新陈代谢.葡萄糖-6-酸盐酶是什么结构-功能的结构-功能.

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