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用于生物成像的功能光体的年代发展

Subrata Munan¹, Young-Tae Chang², Animesh Samanta¹

¹Molecular Sensors and Therapeutics (MST) Research Laboratory, Department of Chemistry, School of Natural Sciences, Shiv Nadar Institution of Eminence, Delhi NCR, NH 91, Tehsil Dadri 201314, Uttar Pradesh, India. animesh.samanta@snu.edu.in.

Chemical communications (Cambridge, England)

|December 14, 2023

概括

本综述总结了用于细胞成像和传感的传统和新型功能光体. 在2007-2022年间开发的新型光体为生物成像应用提供了先进的光学特性.

科学领域:

化学生物学化学生物学
生物技术是生物技术.
光学成像技术的成像

背景情况:

功能性光体对于传感和细胞成像至关重要.
显微镜和探针开发的进步提高了生物成像能力.
缺乏对新开发的光体的简要概述.

研究的目的:

系统地审查传统和新型光体的时间发现.
探索2007年至2022年间开发的十种新型核心光体.
讨论它们在生物成像和潜在的生物医学研究中的应用.

主要方法:

关于传统和新型光体的文献综述.
对新型光体的光学特性和应用的分析.
讨论化物开发的挑战和前景.

主要成果:

传统光体的概述 (可见到近红外).
详细探索十种具有先进光学特性的新型核心光体.
用于成像生物分子 (ROS,RNS,蛋白质) 和微环境 (pH,粘度) 的新型光体的插图.

结论:

新的光体为生物成像提供了先进的光学特性.
这些探测器为分子相互作用,疾病进展和微环境提供了新的见解.
进一步开发具有生物医学研究的巨大潜力.

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