怀孕期间GLP-1反应:三个月之间的变化和与食欲感觉和通常的能量摄入有关联
Inès Auclair Mangliar1,2,3, Anne-Sophie Plante2,3, Myriam Chabot4
1School of Nutrition, Université Laval, Québec, QC, Canada.
概括
怀孕改变了摄入食物的荷尔蒙调节,血葡萄糖类-1 (GLP-1) 降低,并在晚期三分之一月观察到饥饿感增加. 然而,GLP-1和食欲感觉与妊娠期间的总体能量摄入量存在有限的关联.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 生殖生理学 生殖生理学
背景情况:
- 在怀孕期间,对食物摄入的荷尔蒙调节至关重要,但其三个月的具体变化和与能量平衡的关联需要进一步阐明.
- 类似葡萄糖-1 (GLP-1) 在食欲调节中起着关键作用,但其在怀孕期间的动态变化尚未完全理解.
研究的目的:
- 为了比较产后血葡萄糖类-1 (GLP-1) 响应在怀孕三季度.
- 为了比较整个孕期的食欲后食欲感觉.
- 检查GLP-1水平,食欲感觉和通常的能量摄入量之间的三个月特定关联.
主要方法:
- 一组26名参与者在每个三个月接受了评估,在禁食后食用标准餐.
- 血GLP-1水平通过ELISA在禁食和多个食后时间点测量.
- 用视觉模拟尺度评估食欲感受,通过24小时的饮食回忆评估能量摄入量.
主要成果:
- 与第一季度相比,食后GLP-1反应在第二和第三季度显著下降.
- 增加的饥饿感和渴望吃饭的愿望在第3个三个月报告,而不是第一个.
- 虽然GLP-1与晚期三季度的食后腹感相关,但GLP-1,食欲和通常的能量摄入量之间没有发现显著的关联.
结论:
- 在怀孕期间,GLP-1分泌和食欲感受表现出显著的三个月特异性变化.
- 尽管有这些变化,GLP-1,食欲感知和怀孕期间总体能量摄入之间的直接联系仍然很弱.
- 需要进一步的研究,才能充分了解影响母亲能量平衡的荷尔蒙和感官因素的复杂相互作用.
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