面对面:使用异二胺和怀孕结果
Zeynep Tırmıkçıoğlu1, Aslı Tatlıparmak2
1Clinical Pharmacology and Toxicology Unit, Izmir Ataturk Research Hospital, Izmir, Turkey.
International journal of dermatology
|December 14, 2023
概括
在怀孕期间,系统性异二胺暴露没有显示出重大出生缺陷的证据. 然而,对胎儿形的恐惧往往导致选择性妊娠终止,这突出了对孕妇的重大担忧.
科学领域:
- 药理学和毒理学 药理学和毒理学
- 生殖健康 生殖健康
- 皮肤病学 皮肤病学
背景情况:
- 伊索特里诺因是严重的常见治疗方法,指南建议在怀孕前一个月停止使用.
- 关于暴露胎儿中异二因的绝对致性风险的准确数据仍然有限.
- 这项研究评估了在2016年至2020年期间寻求药物风险评估的孕妇对异丁氨酸暴露的评估.
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