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Updated: Jul 1, 2026

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一种随机多重CRISPRi-Seq方法用于识别基因的关键组合

Nicole A Ellis1, Kevin S Myers2,3, Jessica Tung1

  • 1Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States.

eLife
|December 14, 2023
PubMed
概括

一种新的多重,随机的CRISPR干扰测序 (MuRCiS) 方法快速识别病原体中的基本基因组合. 这种方法揭示了Legionella pneumophila中冗余的毒性基因,这对于宿主-病原体相互作用至关重要.

关键词:
流感性肺炎病毒 (Legionella pneumophila) 是一种流感性肺炎病毒.遗传学 遗传学 遗传学 是一个基因组学就是基因组学.传染病是一种传染性疾病.细胞内病原体 细胞内病原体莱吉欧内拉肺炎菌 (Legionella Pneumophila) 是一种病毒.微生物学的微生物.转移移位的效应者.

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