关于证据的规范性 - - 科学哲学和"VALIDATE"项目的教训
P Refolo1, D Sacchini, B Bloemen
1Research Center for Clinical Bioethics and Medical Humanities, Università Cattolica del Sacro Cuore, Rome, Italy. dario.sacchini@unicatt.it.
European review for medical and pharmacological sciences
|December 14, 2023
概括
随机临床试验 (RCT) 对基于证据的医学 (EBM) 至关重要,但其发现必须考虑背景和潜在价值. 了解科学知识的规范性对于强大的医疗技术评估 (HTA) 至关重要.
科学领域:
- 科学哲学的哲学科学哲学
- 医疗技术评估 (HTA) 是指对医疗技术进行评估.
- 基于证据的医学 (EBM)
背景情况:
- 随机临床试验 (RCT) 传统上被视为产生医学证据的黄金标准.
- 关于RCT结果的解释存在误解,经常忽视它们的上下文和价值载荷性质.
- 人们对科学知识生产中固有的规范性意识往往缺乏.
研究的目的:
- 强调科学知识生产中固有的规范性.
- 突出规范性在进行随机临床试验 (RCT) 中的作用.
- 强调规范性在卫生技术评估 (HTA) 过程中的重要性.
主要方法:
- 根据科学哲学原则进行分析.
- 纳入欧洲项目"VALIDATE" (医疗技术评估中的价值) 的见解.
- 在HTA培训中利用政治学和伦理学的教训.
主要成果:
- 科学知识,包括RCT和HTA,是价值和理论负载 (规范) 的.
- 实验室试验结果不是孤立的,而是存在于特定的价值环境中.
- 在VALIDATE项目中,通过跨学科的见解来优化HTA培训.
结论:
- 承认证据的规范性对于准确解释RCT和HTA至关重要.
- 整合哲学,伦理和政治科学的观点,增强了HTA.
- 解决这些见解可以帮助在健康技术评估中应对未来的挑战.
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