糖尿病足与PAD的临床特征和风险因素
1Department of Wound Repairment, The Second Affiliated Hospital of Dalian Medical University, Ganjingzi District, Dalian City, Liaoning Province, China. whuan525@sina.com.
European review for medical and pharmacological sciences
|December 14, 2023
概括
糖尿病足与周围动脉疾病 (PAD) 相结合,与年龄较大,严重的,吸烟和血糖控制不佳有关. 在这些患者中,心压升高 (DBP) 可能会提供对PAD的保护.
科学领域:
- 内分泌学和新陈代谢学
- 血管外科 血管外科
- 糖尿病学 糖尿病学
背景情况:
- 糖尿病足 (DFU) 是糖尿病的一个重要并发症.
- 周围动脉疾病 (PAD) 经常与DFU共存,使治疗和预后复杂化.
- 在DFU患者中确定PAD的风险因素对于有效的管理至关重要.
研究的目的:
- 分析患有糖尿病足 (DFU) 和同时存在的外周动脉疾病 (PAD) 的患者的临床特征.
- 在被诊断为DFU的患者中识别与PAD存在相关的风险因素.
主要方法:
- 从2018年10月到2021年2月,对120名DFU患者进行了回顾性研究.
- 患者被分为患有PAD和没有PAD的组.
- 单变量和二进制物流回归分析以确定PAD的风险因素.
主要成果:
- PAD组的患者比例较高,年龄≥60岁,瓦格纳4-5级,吸烟史.
- 患有PAD的患者有较低的透析血压 (DBP),但较高的C反应蛋白 (CRP),中性粒细胞与淋巴细胞的比率 (NLR) 和糖化血红蛋白 (HbA1c) 水平.
- 在DFU患者中,PAD的危险因素包括年龄≥60岁,高瓦格纳度,吸烟,CRP,NLR和HbA1c升高;升高的DBP是一个保护因素.
结论:
- 患有PAD的DFU患者表现出血压控制不良,疾病持续时间长,脚-手腕指数 (ABI) 较低.
- 在DFU患者中,PAD的主要风险因素是年龄较大,严重的,吸烟以及炎症/血糖标志物 (CRP,NLR,HbA1c) 的升高.
- 在糖尿病足的背景下,增加的DBP被确定为PAD的保护因素.
相关概念视频
01:11Pulse Assessment Sites
1.1K
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
1.1K
01:15Diabetes: Symptoms, Diagnosis, and Complications
554
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
554
01:30Peptic Ulcer Disease I: Introduction
176
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
176
01:20Pathophysiology of Diabetes
949
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
949
01:27Assessment of the Cardiovascular System III: Palpation
342
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
342
01:29Cardiovascular System Abnormal Findings I: Inspection and Palpation
404
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
Abnormal findings observed during an inspection
404