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精子可以增强抗结核药物的活性

Carine Sao Emani1, Norbert Reiling1,2

  • 1Microbial Interface Biology, Research Center Borstel, Leibniz Lung Center , Borstel, Germany.

Microbiology spectrum
|December 14, 2023
PubMed
概括

精子 (Spm) 在Mycobacterium tuberculosis (M.tb) 中产生反应性氧物种 (ROS),增强结核病药物的疗效. 这种毒性较低的化合物可能是未来结核病治疗方案的宝贵补充.

关键词:
结核菌菌菌 (M.tb) 是一种贝达基林 (BDQ) 是一种烯氧化 (CuOOH) 的使用异化 (INH) 是一种准-氨基酸 (PAS) 的使用.反应性氧物种 (ROS) 是一种反应性氧物种.里芬素 (RIF) 是一种精子蛋白 (Spm) 是一种结核病 (TB) 是一种疾病.

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