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Updated: Jul 8, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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碰撞诱导的展开,协奏MS,自下而上的蛋白质学和相互作用学用于在本地表面质谱中识别蛋白质复合体

Raul A Villacob1, Neda Feizi1, Sarah C Beno1

  • 1Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States.

Journal of the American Society for Mass Spectrometry
|December 14, 2023
PubMed
概括

这项研究引入了一种新的多端方法,结合了原生表面质谱 (NSMS),并联质谱和自下而上的蛋白质组学,以直接从生物表面增强蛋白质特征,克服电离化的挑战.

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