对人类羊膜细胞的转录组研究确定了与唐氏综合征发育性发育不良相关的枢纽基因

Zhenglong Guo1,2, Hai Xiao1,2, Wenke Yang1,2

  • 1Henan Provincial Key Laboratory of Genetic Diseases and Functional Genomics, National Health Commission Key Laboratory of Birth Defects Prevention, Medical Genetic Institute of Henan Province, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, China.

Aging
|December 14, 2023
PubMed
概括

唐氏综合征 (DS) 涉及额外的染色体21 (HSA21),导致发育问题. 这项研究发现DS细胞的基因表达改变,将HSA21基因与发育表型联系起来,并提供潜在的治疗点.

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