过口内镜甲状腺切除术前庭治疗方法 (TOETVA) 中的并发症和转化结果:一个回顾性多中心倾向性得分匹配的队列研究
Ziya Karimov1, Seok-Mo Kim2, Yigit Turk3
1Medicine Program, Ege University Faculty of Medicine, Izmir, Turkey.
Updates in surgery
|December 14, 2023
概括
穿口内镜甲状腺切除术与前庭治疗方法 (TOETVA) 是一种没有痕的甲状腺手术. 这项国际研究发现,在使用倾向性得分匹配时,在TOETVA后没有出现并发症或转换的显著风险因素.
科学领域:
- 手术瘤学手术瘤学
- 内分泌手术 内分泌手术
- 最少侵入性的手术
背景情况:
- 穿越口腔内镜甲状腺切除术以前体方法 (TOETVA) 为传统的开放甲状腺手术提供了一个无痕的替代方案.
- 确定并发症和转化预测因素对于优化TOETVA.VA患者的治疗结果至关重要.
研究的目的:
- 调查 TOETVA 期间与并发症和转化相关的潜在风险因素.
- 分析人口统计和手术数据,以确定TOETVA中不良事件的预测因素.
主要方法:
- 国际回顾性研究涉及406名接受TOETVA的成年患者.
- 收集的数据包括人口统计,手术前,手术内和手术后的变量.
- 倾向性得分匹配 (PSM) 用于控制患有并发症/转化和没有并发症/转化的患者之间的混因素.
主要成果:
- 在2.7%的患者中出现并发症.
- 统一分析发现高BMI,较大的瘤大小,增加的甲状腺体容量和较长的操作时间与并发症有关.
- 高龄,高BMI和较长的操作时间与单变量分析中的转换有关,但这些关联在PSM后失去意义.
结论:
- 在倾向性得分匹配后,这项研究的数据没有表明TOETVA中出现并发症或转换的显著独立风险因素.
- 可能需要进一步的研究,以充分阐明无痕甲状腺手术中的风险因素.
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