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Updated: Jul 8, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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病原性细菌在感染期间经历了普遍的RNA聚合酶逆行

Kaitlyn R Browning1, Houra Merrikh1

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

mBio
|December 14, 2023
PubMed
概括

主体防御阻碍了细菌RNA聚合酶 (RNAP),增加了突变发生. 这项研究揭示了沙门氏菌感染期间普遍存在的RNAP逆行,突出了它在细菌进化和抗菌素耐药性方面的作用.

关键词:
在PIC-seqqq.在RNAP的逆向跟踪中.沙门氏菌 (Salmonella enterica) 已经成为一种常见的疾病.主体-病原体相互作用

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