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Updated: Jul 8, 2025

Quantification of Monocyte Chemotactic Activity In Vivo and Characterization of Blood Monocyte Derived Macrophages
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核酸感应通过偏向的凝血因子VIIa信号传递促进炎症单细胞迁移

Hortensia Zelaya1,2, Kristin Grunz1, T Son Nguyen1

  • 1Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, Germany.

Blood
|December 14, 2023
PubMed
概括

骨髓细胞因子VIIa (FVIIa) 通过蛋白酶激活受体2 (PAR2) 发出信号,在病毒RNA暴露后驱动肺炎. 这一途径对免疫细胞的招募和迁移至关重要,这表明了对血栓炎症的新治疗点.

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