关于败血症治疗的系统审查的方法质量:一个横截面研究
Leonard Ho1, Xi Chen2, Yan Ling Kwok1
1Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
The American journal of emergency medicine
|December 14, 2023
概括
大多数关于败血症治疗的系统审查 (SR) 缺乏严格的方法,影响临床实践. 提高SR质量对于可靠的基于证据的败血症护理至关重要.
科学领域:
- 基于证据的医学是基于证据的医学.
- 临床研究方法论临床研究方法论
- 卫生科学 卫生科学
背景情况:
- 系统性审查 (SRs) 对于合成有关败血症治疗的证据至关重要.
- SRs的方法质量可能会有所不同,这可能会限制其临床适用性.
- 评估最近关于败血症治疗的SRs的严格性是必要的,以确定质量差距.
研究的目的:
- 评估对败血症治疗方法的系统审查的方法质量.
- 确定最近SRs中常见的方法缺陷.
- 探索与这些评论质量相关的因素.
主要方法:
- 搜索了MEDLINE,EMBASE和Cochrane数据库,搜索了2018-2023年发表的关于败血症治疗的SRs.
- 使用AMSTAR 2 (评估系统性审查的测量工具) 来评估方法质量.
- 使用后勤回归来分析文献特征和质量评级之间的关联.
主要成果:
- 在102个SR中,只有2.0%的质量高;87.3%的质量极低.
- 在偏差风险评估 (31.4%) 和全面搜索 (15.7%) 方面发现了显著的缺陷.
- 发表在具有更高影响因子的期刊与更高的方法质量相关 (aOR 1.19).
结论:
- 最近对败血症治疗方法的系统审查显示,方法质量不令人满意.
- 未来的SR必须优先考虑关键的方法方面,如偏见评估和搜索策略.
- 为医疗保健专业人员和证据用户推加强批判性评估培训.
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