在农村初级保健诊所的阿片类药物使用障碍患者中同时出现的物质使用障碍
Yuhui Zhu1, Laura-Mae Baldwin2, Larissa J Mooney3
1Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90024, United States of America.
Journal of substance use and addiction treatment
|December 14, 2023
概括
农村诊所中患有阿片类药物使用障碍 (OUD) 和并发性物质使用障碍 (SUD) 的患者获得了更多的医疗保健服务. 这些人患有型肝炎和精神健康障碍的比率更高,突出了对量身定制护理的需求.
科学领域:
- 公共卫生 公共卫生
- 初级医疗保健医学 一级医疗保健医学
- 成精神病学成精神病学
背景情况:
- 在阿片类药物使用障碍 (OUD) 患者中,同时出现的物质使用障碍 (SUD) 与损伤,过量使用风险和死亡率的增加有关.
- 了解OUD患者的特征,包括并发SUD和无并发SUD,对于有效的农村医疗保健服务至关重要.
研究的目的:
- 检查农村初级保健机构中OUD患者的人口和临床特征.
- 为了比较只有OUD的患者与OUD和同时出现的兴奋剂使用障碍 (OUD + StUD) 或其他SUD (OUD + 其他) 的患者.
- 评估这些患者群体中医疗保健服务的使用情况.
主要方法:
- 来自六个农村初级保健诊所和一个远程医疗供应商的电子健康记录 (EHR) 数据的二次分析.
- 包括在2019年10月至2021年1月期间访问参与诊所的OUD成年患者.
- 根据诊断,将患者分为OUD Only,OUD + StUD和OUD + 其他组.
主要成果:
- 确定了1164名OUD患者,72.6%仅有OUD,11.5%OUD + StUD,15.9%OUD + 其他.
- OUD + StUD组表现出C型肝炎 (25.4%) 和精神健康障碍 (78.4%) 的最高率.
- 同时出现SUD (OUD + StUD和OUD + 其他) 的患者更有可能接受远程医疗,行为健康和OUD (MOUD) 服务的药物治疗.
结论:
- 在农村初级保健中,超过27%的OUD患者同时出现SUD.
- 这些患有并发性SUD的患者使用了更多的医疗保健服务,而不是仅使用OUD的患者.
- 需要进一步的研究来探索与OUD患者的医疗保健服务变异相关的结果,同时出现SUD.
相关概念视频
Opioid Analgesics: Morphine and Other Natural Cogeners
253
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
253
Substance Use Disorders Affecting Sleep
169
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
169
Prescription, Nonprescription and Orphan Drugs
736
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
736
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
208
Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
208
Opioid Analgesics: Synthetic and Semisynthetic Opioids
302
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
302
Drug Abuse and Addiction: Pharmacological Phenomena
486
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
486


