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异常的上皮细胞相互作用促进食道状细胞癌的发展和进展

Liping Chen1, Shihao Zhu1, Tianyuan Liu1

  • 1Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

Signal transduction and targeted therapy
|December 14, 2023
PubMed
概括

由TP53突变和DNP63驱动的异常EFNB1-EPHB4相互作用触发了上皮-介质细胞过渡 (EMT) 和食道癌的扩散. 这一途径对于癌症的发展和进展至关重要.

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