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Updated: Jul 8, 2025

Evaluating In Vitro DNA Damage Using Comet Assay
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Published on: October 11, 2017

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将组合性药物效应映射到DNA损伤反应激酶抑制剂

Hanrui Zhang1, Julian Kreis2, Sven-Eric Schelhorn2

  • 1Department of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.

Nature communications
|December 14, 2023
PubMed
概括

这项研究对62个癌细胞系的87种药物进行了选,确定了针对ATR,ATM和DNA-PK等DNA损伤反应 (DDR) 激酶的协同药物组合,以加强癌症治疗.

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