副结膜出血与出血性疾病之间的关联:一项全国性基于人口的研究
In Hwan Hong1,2, Bum-Joo Cho1,3,4, Se Hyun Choi5,6
1Department of Ophthalmology, Hallym University College of Medicine, Chuncheon-si, Gangwon-do, Republic of Korea.
Scientific reports
|December 14, 2023
概括
副结膜出血 (SCH) 是一种常见的眼睛疾病. 这项研究发现,SCH与脑内出血和胃肠道出血的风险较低有关,特别是在老年女性中.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 胃肠病学 胃肠病学
背景情况:
- 副结膜下出血 (SCH) 是一种可见的良性眼睛疾病,需要医疗访问.
- 关于SCH和心血管疾病的先前研究存在,但其与出血障碍的联系仍在争论中.
- 了解SCH和重大出血事件之间的关联对于临床管理至关重要.
研究的目的:
- 调查副结膜出血 (SCH) 与随后脑内出血 (ICH) 和胃肠道 (GI) 出血的风险之间的关联.
- 分析与对照人群相比,SCH患者的ICH和胃肠道出血的发病率和风险因素.
- 确定可能影响观察到的关联的人口统计学子组,如年龄和性别.
主要方法:
- 一项全国性的队列研究利用了来自国家医疗保险服务-国家样本队列 (2006-2015) 的数据.
- 使用诊断代码识别了副结膜出血 (SCH).
- 倾向性得分 (PS) 匹配分析比较了36772名SCH患者和147088名对照人群中ICH和GI出血的发生率.
主要成果:
- 副结膜出血 (SCH) 与大脑内出血 (ICH) (HR=0.76) 和胃肠道 (GI) 出血 (HR=0.816) 的风险显著降低.
- 这种保护性关联在女性和50岁或以上的个人中更为明显.
- 在男性或年轻年龄组中没有观察到降低风险.
结论:
- 副结膜出血 (SCH) 不会增加随后脑内出血 (ICH) 或主要胃肠道 (GI) 出血的风险.
- SCH与ICH和胃肠道出血的发病率降低有关,特别是在老年女性中.
- 这些发现表明,SCH在特定的人口群体中可能对重大出血事件起着保护作用.
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