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Twnbiome:一个健康的台湾肠道微生物群的公共数据库

Amrita Chattopadhyay¹, Chien-Yueh Lee², Ya-Chin Lee³

¹Bioinformatics and Biostatistics Core, Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.

BMC bioinformatics

|December 15, 2023

概括

Twnbiome是台湾肠道微生物组的新数据库,为研究人员提供了一个用户友好的平台来分析微生物数据. 这个资源有助于了解各种健康研究的肠道微生物群.

科学领域:

微生物学微生物学
生物信息学是一种生物信息学.
基因组学就是基因组学.

背景情况:

下一代测序 (NGS) 使细菌基因组研究变得更容易获得和更具成本效益.
NGS能够实现高通量测序,识别出许多以前未知的微生物物种.
分析NGS数据需要复杂的生物信息管道和大量的计算资源,这对许多研究人员来说是一个障碍.

研究的目的:

为台湾人口建立Twnbiome,一个公共的肠道微生物群数据库.
从健康的台湾人群中提供基线肠道微生物群参考小组.
为临床医生和生物学家提供可访问的分析管道,以解释微生物组数据.

主要方法:

开发一个公共肠道微生物群数据库 (Twnbiome),使用来自健康台湾受试者的数据.
创建一个综合分析管道,用于用户数据上传和结果下载.
实现了一个用户友好的界面,具有可定制的图表和可下载的表.

主要成果:

Twnbiome为台湾的肠道微生物研究提供了有价值的参考数据集.
综合管道为非生物信息学用户简化了复杂的NGS数据分析.
数据库和管道是互动的,信息的,和用户友好的.

结论:

台湾生物群是台湾人群中微生物群研究的重要资源.
该平台使临床医生和研究人员能够进行病例控制研究,并有效地解释微生物群数据.
可访问的分析工具促进了对肠道微生物组研究的更广泛参与.

关键词:

我们的肠道微生物群.身体健康的受试者公共数据库公共数据库.台湾人口台湾人口

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