低血中心电图异常的患病率和预后价值:一个多中心队列研究
Helene Kildegaard1, Mikkel Brabrand2,3, Jakob Lundager Forberg4,5
1Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.
低血是常见的,与心电图变化有关. 然而,这些心电图 (ECG) 异常并不是低血压患者不良结果的强有力的预测因素.
科学领域:
- 心脏病学 心脏病学
- 内部医学 内部医学
- 临床电生理学 临床电生理学
背景情况:
- 低血清是住院患者经常发现的症状.
- 电心电图 (ECG) 异常经常在低血中观察到.
- 这些心电图变化在低血压患者的预后意义仍然不清楚.
研究的目的:
- 为了确定心电图异常在低血压患者的患病率.
- 评估心电图异常对低血短期不良事件的预后价值.
主要方法:
- 在79599名患有低水平的成年患者中进行了多中心队列研究.
- 分析与水平相关的心电图变量 (心率,QRS持续时间,QTc间隔,ST压力,T波变化).
- 倾向性得分匹配用于比较特定心电图异常和无特定心电图异常的患者之间的结果 (7天死亡率,ICU入院).
主要成果:
- 降低水平与增加的心电图异常相关.
- 40%的低血压患者表现出心电图异常,包括T波平整 (27%),ST压力 (16%),和QTc延长 (14%).
- 虽然一些心电图变化表明轻度低血的死亡风险增加,但整体预后值有限,风险估计与eukkalemic患者相似.
结论:
- 在低血压患者中,心电图异常很普遍.
- 这些心电图发现是短期不良事件的不良预后标志物.
- 目前的标准护理可能会减轻低血中心电图异常的预后影响.
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