双胞胎怀孕中的胎液量和怀孕结果:系统性审查和元分析
Dayna Whitcombe1, Everett Magann1, Susan Steelman2
1Department of Obstetrics & Gynecology University of Arkansas for Medical Sciences Little Rock Arkansas USA.
Australasian journal of ultrasound in medicine
|December 15, 2023
概括
这次审查没有发现怀孕或新生儿结局对双胞胎怀孕与异常的羊水体积 (AFV) 的显著差异. 需要更多的研究来了解AFV.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 周围生理学 周围生理学
- 双胞胎怀孕研究 双胞胎怀孕研究
背景情况:
- 胚胎液体体积 (AFV) 异常,如橄水和多水,可以影响怀孕的结果.
- 双胞胎怀孕在管理AFV和评估相关风险方面存在独特的挑战.
- 关于双胞胎怀孕中AFV异常的具体影响的研究有限.
研究的目的:
- 系统地审查和元分析胎液体体积 (AFV) 异常 (oligohydramnios或polyhydramnios) 与双胞胎怀孕中的怀孕/新生儿结果之间的关联.
- 确定当前关于双胞胎怀孕中AFV的文献中的差距.
主要方法:
- 系统审查已出版和灰色文献.
- 包括以英语为对照组的前性和后性研究.
- 排除异常胎儿,特定复杂的单双胞胎并发症和治疗干预措施.
主要成果:
- 对四项纳入研究的分析显示,在早产,32周前分娩,低带pH值,死产,新生儿死亡,新生儿重症监护室入院或怀孕年龄较小的婴儿中,没有统计学上显著的差异.
- 从每项结果的两项研究中汇集的数据显示,没有显著的关联.
结论:
- 目前的证据表明,双胞胎怀孕异常AFV的主要不良结果没有显著差异.
- 在1946年至2020年之间发表的研究令人担忧的缺乏,突出了了解AFV在双胞胎怀孕结果中的作用的关键差距.
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