18个月的低风险中度到晚期早产婴儿的神经发育结果
Mary Anne Ryan1,2, Deirdre M Murray1,2, Eugene M Dempsey1,2,3
1INFANT Centre, University College Cork, Cork, Ireland.
Frontiers in pediatrics
|December 15, 2023
概括
适度到晚期早产 (MLP) 婴儿在18个月时表现出较差的神经发育结果,与按时出生的婴儿相比. 早期监测MLP婴儿发育对于识别潜在问题至关重要.
科学领域:
- 新生儿研究新生儿研究
- 发育儿科 发育儿科
- 神经科学是一个神经科学.
背景情况:
- 中度到晚期早产 (MLP) 出生 (32-36+6周妊娠年龄) 占每年早产的80%.
- 了解这个大群体的神经发育结果是必不可少的.
研究的目的:
- 为了评估18个月的健康,低风险的MLP婴儿的神经发育结果.
- 为了比较MLP婴儿的神经发育与健康的,按期出生的对照.
主要方法:
- 一个单一中心的观察性研究,将健康的MLP婴儿与健康的术语控制 (TC) 婴儿进行比较.
- 在18个月时使用格里菲斯III神经发育评估.
主要成果:
- 与TC婴儿相比,MLP婴儿在眼手协调,个人/社会/情绪发展,毛细运动发展和一般发展方面得分明显较低 (p < 0.001).
- 在MLP婴儿中,学习基础得分也明显较低 (p = 0.004).
- 两组之间语言和沟通子表得分没有显著差异 (p = 0.107).
结论:
- 患有MLP的婴儿有较高的潜在神经发育结果的风险.
- 在这个处于风险的早产人口中,加强对神经发育轨迹的监测是有必要的.
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