慢性病作为老年人中创伤性脑损伤预后不良的预测因素:一个病例对照研究
Haoyang Mo1,2, Fan Fan1,2, Jian Liu1,2
1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Frontiers in neurology
|December 15, 2023
概括
创伤性脑损伤 (TBI) 患者患有并发性慢性病 (CKD) 经历更糟糕的结果. 在TBI患者中,CKD与格拉斯哥昏迷表得分较低和感染增加有关,这表明预后较差.
科学领域:
- 神经学 神经学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
背景情况:
- 创伤性脑损伤 (TBI) 是发病率和死亡率的重要原因,特别是在老年人中.
- 慢性病 (CKD) 影响全球人口的很大一部分,并与死亡率的增加有关.
- 慢性病共发病对TBI预后的影响仍然不太清楚.
研究的目的:
- 调查TBI患者的临床结果,并发性CKD.
- 确定与TBI患者的慢性脏病预后不佳相关的风险因素.
主要方法:
- 进行了一项病例控制研究,将11名患有CKD的TBI患者与27名没有CKD的TBI患者进行比较.
- 患者因年龄,性别和入院格拉斯哥昏迷表 (GCS) 评分而匹配.
- 分析了临床结果,包括GCS,ICU停留,住院费用和感染率.
主要成果:
- 慢性结核创伤组的出院GCS得分明显较低 (7.1比13.1,p<0.01) 和在医院获得的感染率更高 (54.4%比7.4%,p<0.01).
- 虽然ICU住院和住院费用在CKD组中较高,但这些差异在统计学上并不显著.
- 后勤回归确定了晚年,低入院GCS,高血尿素和肌素作为不良神经预后的预测因素.
结论:
- 并发性CKD与TBI患者的预后较差有关.
- 慢性瘤会对神经恢复产生负面影响,并增加TBI后的传染性并发症.
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