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Updated: Jul 8, 2025

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删除CTCF会改变人类iPSC的多能性和DNA甲基化特征

Deepika Puri1,2, Catharina Maaßen1,2, Monica Varona Baranda1,2

  • 1Institute for Stem Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.

Frontiers in cell and developmental biology
|December 15, 2023
PubMed
概括

CCCTC-结合因子 (CTCF) 对于维持多能性和指导细胞分化至关重要. 切除CTCF损害了外皮发育,同时促进了内皮半皮系,揭示了它在细胞命运决定中的作用.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?在CTCF中,CTCF是指CTCF.通过DNA甲基化.在IPSC中,您可以使用IPSC.不同化的差异化差异化.多能性的多能性.干细胞是干细胞的组成部分.

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