对双出口右心室单胞胎双胞胎异调的综合多态学分析

Zhen Liu1,2, Nana Li1,2, Xiaoyu Pan3,4

  • 1National Center for Birth Defect Monitoring of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

概括

表观遗传变化,特别是全球低甲基化,与诸如双出口右心室 (DORVs) 等先天性心脏缺陷 (CHDs) 有关. 这项针对不和双胞胎的多组学研究确定了参与心血管疾病发展的关键基因和途径.

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