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Updated: Jul 8, 2025

Single-cell Screening Method for the Selection and Recovery of Antibodies with Desired Specificities from Enriched Human Memory B Cell Populations
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在抗体轻链可变域中,存在多个聚合途径的动态证据

Sherry Wong1, Madeline E West1, Gareth J Morgan1

  • 1Boston University Amyloidosis Center, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.

Protein science : a publication of the Protein Society
|December 15, 2023
PubMed
概括

抗体轻链蛋白聚合,与轻链氨基粉症相关,显示复杂的动力学. 蛋白质度和播种影响聚合率,这表明多种物种有助于疾病病理.

关键词:
在AL氨基粉症症.聚合动力学 聚合动力学粉样蛋白纤维的纤维.抗体具有可变域的抗体.蛋白质的错误折叠 蛋白质的错误折叠系统性轻链氨基粉症.

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