围产期不良事件和母亲怀孕期间体重变化:基于人口的观察性研究
Eyal Cohen1,2,3,4, Longdi Fu2, Hilary K Brown2,4,5
1Department of Pediatrics and Edwin S.H. Leong Center for Healthy Children, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
概括
婴儿的逆境可能会影响母亲的健康. 新生儿经历围产期不良事件的妇女在怀孕期间体重增加,并更有可能进入更高的体重指数类别.
科学领域:
- 生殖健康 生殖健康
- 围产儿医学 围产儿医学
- 孕产妇和婴儿的健康
背景情况:
- 母亲的自我照顾,例如在怀孕后保持健康的体重,在婴儿遭遇逆境后可能会受到损害.
- 周产期不良事件可能导致母亲忽视自己的健康,影响妊娠期间的体重变化.
- 了解怀孕期间的体重增加对于在具有挑战性的分娩结果后评估母亲健康至关重要.
研究的目的:
- 调查第一胎儿周围不良事件与母亲妊娠期间体重增加之间的关联.
- 为了确定不良周产期结果是否会影响母亲在怀孕之间增加身体质量指数 (BMI) 类别的可能性.
主要方法:
- 加拿大安大略省的一项以人口为基础的观察性研究包括了192,154名初怀孕妇女,分别连续两次单子分娩.
- 评估了妊娠间净体重增加和转移到更高BMI类别的几率.
- 妇女的婴儿经历了不良事件 (围产死亡,早产,严重的新生儿发病率,先天性异常,神经障碍) 和那些婴儿没有经历的妇女之间的比较.
主要成果:
- 围产死亡与3.5公斤更高的孕产妇体重增加有关. 过早分娩 (<32周) 与3.2公斤的体重增加有关,而晚期过早分娩也显示出显著的体重增加.
- 患有重症新生儿发病的婴儿与1.2公斤的孕产妇体重增加有关.
- 转移到更高的BMI类别的调整后的几率比率 (aOR) 在产前死亡 (aOR=1.27),早产<32周 (aOR=1.21) 和严重新生儿发病率 (aOR=1.11) 后升高.
结论:
- 初生婴儿的周产期不良事件与母亲在怀孕期间的体重增加有关.
- 经历某些重大周产期不良事件的母亲在怀孕之间更有可能过渡到更高的体重指数类别.
- 这些发现强调了婴儿健康挑战对母亲体重管理和长期健康的潜在影响.
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