追溯评估犬类帕沃病毒病的血液学比率:401例病例
Andrea González-Domínguez1,2, José Ignacio Cristobal-Verdejo3, Clara López-Espinar4
1Veterinary Teaching Hospital of the Catholic University of Valencia-Emergency and critical care, Valencia, Spain.
Journal of veterinary internal medicine
|December 15, 2023
概括
血小板与淋巴细胞的比率 (PLR) 可以帮助预测患有犬类帕沃病毒 (CPV) 的狗的结果. 在入院时PLR较高表明CPV患者的预后较差.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 血液学 血液学 血液学
- 狗的健康 狗的健康
背景情况:
- 狗病毒 (CPV) 的预后指标对于有效的治疗策略至关重要.
- 中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR) 和单细胞与淋巴细胞的比率 (MLR) 在CPV中的实用性尚未先前确定.
研究的目的:
- 调查入院血液学比率 (NLR,PLR,MLR) 与CPV.狗的临床结果之间的关联.
- 确定这些比率是否可以预测CPV病例的存活率或住院时间.
主要方法:
- 一项回顾性多中心队列研究包括401只被诊断患有CPV的狗.
- 收集的数据包括信号,入院时的全血细胞计,住院时间和结果.
- 统计分析评估了血液学比率与患者结果之间的相关性.
主要成果:
- 与幸存者相比,在未幸存者中观察到显著更高的PLR (P=.003).
- 较低的淋巴细胞计数和较高的单细胞计数也与不存活有关.
- 在住院时间和评估的血液学比率或总白细胞计数之间没有发现显著的关联.
结论:
- 住院时的血小板与淋巴细胞比率 (PLR) 可能作为犬类帕沃病毒病的疾病严重程度的有价值的预后标志物.
- 进一步的研究可以探索将PLR纳入CPV管理的临床决策.
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