双侧鼻炎,视网膜周围炎和视神经炎与非骨中枢神经系统的细菌相结合
Tianyu Liu1, Apoorv P Chebolu1, Caroline W Chung1
1Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania; and.
Retinal cases & brief reports
|December 15, 2023
概括
在桃体外的一种罕见的中枢神经系统生殖瘤导致了双边脑膜炎,视神经炎和视网膜周炎. 眼部症状在为生殖瘤进行化疗后得到改善.
科学领域:
- 神经瘤学神经瘤学
- 眼科医生 眼科 眼科
- 神经学 神经学
背景情况:
- 中枢神经系统 (CNS) 的胚芽瘤是罕见的瘤.
- 中枢神经系统生殖瘤的眼部表现不常见,特别是部区域以外的表现.
- 这种病例突出显示了一种非部中枢神经系统生殖瘤,呈现出明显的眼部炎症.
研究的目的:
- 报告双边脑膜炎,视网膜周围炎和视神经炎的病例.
- 为了将这些眼部发现与非状腺中枢神经系统生殖瘤联系起来.
- 讨论诊断和治疗方面的影响.
主要方法:
- 病例报告详细介绍了一名32岁的男性患者.
- 眼科检查包括视觉敏度,色彩视觉,瞳孔反应, funduscopy,光学连贯断层扫描 (OCT),和光素血管学 (FA).
- 大脑和轨道的磁共振成像 (MRI),随后进行大脑活检以确认他的病理学.
主要成果:
- 患者呈现的视力敏度下降,色彩视力异常,光盘胀与周周静脉覆盖和"水滴滴"排泄物.
- OCT显示内液和玻璃体不透明;FA显示光盘泄漏.
- 核磁共振扫描显示了周周结膜病变和视神经/外皮增强,通过活检确认为中枢神经系统生殖瘤. 眼部症状通过化疗得到缓解.
结论:
- 非状中枢神经系统生殖瘤可以表现为视神经炎,脑膜炎和视网膜周围炎,包括特征性的"水"排泄物.
- 早期识别这些眼部迹象对于诊断潜在的中枢神经系统生殖瘤至关重要.
- 治疗原发性胚芽瘤导致眼部发现的改善.
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