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Updated: Jul 8, 2025

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes
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在SWI/SNF突变细胞中的DNA损伤反应缺陷及其对免疫反应的影响

Katheryn A G Begg1, Hanna Braun1, Nagham Ghaddar1

  • 1Division of Cancer Biology, The Institute of Cancer Research, London, UK.

DNA repair
|December 15, 2023
PubMed
概括

癌症中失调的SWI/SNF染色体重塑复合物对基因组稳定性和免疫信号产生影响. 本综述探讨了SWI/SNF缺乏如何影响免疫治疗反应,并讨论了治疗策略.

关键词:
在 ARID1A 中.在BAF中,BAF是BAF.这就是CGAS/STING.癌症 癌症 癌症 癌症染色体改造 染色体改造造成的DNA损伤是DNA损伤.修复DNA的修复DNA的修复双链断裂修复 双链断裂修复免疫治疗是一种免疫疗法.新抗原是一种新抗原.这就是PBAF的PBAF.这就是PBRM1的原因.这就是SMARCA4的标志.在 SWI/SNF 中.

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