巴多克索隆甲基通过Nrf2/STING/NF-κB通路打破了M1巨细胞和衰老的细胞核之间的恶性循环

相关实验视频

Updated: Jul 8, 2025

Neuron-Macrophage Co-cultures to Activate Macrophages Secreting Molecular Factors with Neurite Outgrowth Activity
08:52

Neuron-Macrophage Co-cultures to Activate Macrophages Secreting Molecular Factors with Neurite Outgrowth Activity

Published on: March 30, 2018

8.8K

Peng Wang1, Shuo Zhang1, Weijian Liu1

  • 1Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

International immunopharmacology
|December 15, 2023
PubMed
概括

巴尔多克索隆甲基 (CDDO-Me) 打破了M1巨细胞和衰老的细胞核之间的循环,通过向Nrf2/STING/NF-κB通路来减少椎间盘退化 (IDD).

关键词:
巴尔多克索隆甲基椎间盘退化 椎间盘退化巨细胞是一个巨细胞.Nrf2/STING/NF-κBB 在线播放衰老是一种衰老.

更多相关视频

Depletion and Reconstitution of Macrophages in Mice08:50

Depletion and Reconstitution of Macrophages in Mice

Published on: August 1, 2012

39.7K
A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces07:55

A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces

Published on: January 7, 2020

7.4K

相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...
7.4K