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Updated: Aug 16, 2026

Directed Induction of Retinal Organoids from Human Pluripotent Stem Cells
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具有OPA1突变的人类视网膜器官在视网膜质细胞分化和功能方面有缺陷

Qiannan Lei1, Kangjian Xiang1, Lin Cheng1

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China.

Stem cell reports
|December 15, 2023
PubMed
概括

使用3D视网膜器官的自体主导视力缩 (ADOA) 研究揭示了OPA1突变会损害视网膜质细胞 (RGC) 的发育和功能,提供新的治疗途径.

关键词:
自体主导的光学缩.线粒体中的线粒体.视力缩 1 视力缩 1视网膜的质细胞细胞.视网膜的有机体

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Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...