免疫检查点抑制剂诱导的肝损伤
Cathrin L C Gudd1, Roosey Sheth2, Mark R Thursz1,3
1Section of Hepatology and Gastroenterology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Seminars in liver disease
|December 15, 2023
概括
检查点抑制剂 (CPI) 药物彻底改变了癌症治疗,但可以导致与免疫相关的不良事件,如CPI诱导的肝炎 (CPI-H). 本综述涵盖了CPI-H免疫病理学和患者管理.
科学领域:
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 癌症免疫疗法已经与检查点抑制剂 (CPI) 药物取得了进展.
- 慢性肝炎可以引起与免疫相关的不良事件,包括肝炎 (肝炎).
- CPI诱发性肝炎 (CPI-H) 是一种新型的药物诱发性肝损伤.
结论:
- CPI-H是研究和临床关注的关键领域.
- 需要进一步了解CPI-H以优化患者护理.
- 本综述为临床医生和研究人员提供了全面的概述.
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