在基于便免疫化学测试的全国性结肠直肠癌查计划中,结肠镜后结肠直肠癌
Pieter H A Wisse1, Sybrand Y de Boer2, Marco Oudkerk Pool2
1Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands.
Endoscopy
|December 15, 2023
概括
在基于便免疫化学测试 (FIT) 的查中,结肠镜后结肠直肠癌 (PCCRCs) 不常见. 间隔PCCRCs,通常是由于错过的病变,在晚期被诊断出来,突出显示了需要高质量的结肠镜检查的需要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 结肠镜后结肠直肠癌 (PCCRCs) 可以降低结肠直肠癌 (CRC) 查计划的有效性.
- 了解PCCRC对于长期减少CRC发病率至关重要.
- 这项研究将PCCRCs归类为基于便免疫化学测试 (FIT) 的查计划.
研究的目的:
- 在基于FIT的查计划中对在结肠镜检查后诊断的PCCRC进行分类.
- 为了确定不同类别的PCCRC的病因和阶段分布.
主要方法:
- 在2014-2016年期间在荷兰CRC查计划中FIT阳性后进行的结肠镜检查后诊断的PCCRC的分析.
- 使用世界内镜组织的共识对PCCRC进行分类:间隔,非间隔类型A,B和C.
- 对病因的根本原因分析和对不同类别的瘤阶段分布的比较.
主要成果:
- 在116,362次结肠镜检查后的随访期间,共诊断出432例PCCRC.
- 三年PCCRC率为2.7%,其中53.5%被归类为间隔PCCRC.
- 与非间隔类型相比,间隔PCCRC主要是由错过的病变 (73.6%) 引起的,并且在晚期 (53.2%) 更频繁地被诊断出来.
结论:
- 在这个基于FIT的CRC查计划中,3年PCCRC率很低.
- 间隔PCCRC约占所有PCCRC的一半,主要与遗漏病变有关.
- 间隔PCCRCs诊断的先进阶段强调了高质量的结肠镜检查和最佳的息肉检测的重要性.
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