在没有并发症的单胎妊娠中,24小时尿路蛋白质分泌
Yuguo Deng1, Qiulu Wu1, Xiaoyu Tan1
1Department of Obstetrics, Longgang District Maternity and Child Healthcare Hospital of Shenzhen City, Shenzhen, China; Longgang Maternity and Child Clinical Institute, Shantou University Medical College, Shenzhen, China.
American journal of obstetrics and gynecology
|December 15, 2023
概括
这项研究确定了正常怀孕中24小时尿道总蛋白的参考范围,显示水平在整个妊娠期间都在增加. 这些发现有助于监测母亲的健康状况和检测妊娠并发症.
科学领域:
- 产科和妇科 产科和妇科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床化学 临床化学
背景情况:
- 24小时尿道总蛋白质对于评估功能和妊娠并发症至关重要.
- 在正常怀孕期间,24小时尿道总蛋白的参考范围是有限的.
- 确定这些范围对于准确的临床解释至关重要.
研究的目的:
- 在不复杂的单子妊娠中确定24小时尿道总蛋白质分泌的参考范围.
- 按母亲年龄和孕前体重指数分层分层分层蛋白质分泌值.
- 为优化怀孕期间母亲护理提供必要的数据.
主要方法:
- 在中国深对4844名孕妇进行前性队列研究.
- 在三个妊娠季度收集24小时的尿样.
- 使用色度测量方法分析尿道总蛋白质,并确定非参数百分位数的参考范围.
主要成果:
- 24小时尿道总蛋白质分泌量在三个月内显著增加:72.0毫克 (第一),88.0毫克 (第二),108.0毫克 (第三).
- 在年长的母亲 (≥35岁) 和超重或肥胖的母亲中观察到较高的蛋白质水平.
- 所有的增加都是统计学上显著的 (P<0.001对于三个月的变化,P<0.05对于年龄和BMI分层).
结论:
- 这项研究提供了24小时尿道总蛋白质在没有并发症的怀孕中的基本参考值.
- 这些已确定的范围对于准确解释妊娠期间的功能至关重要.
- 了解规范性变化有助于早期发现与怀孕有关的并发症.
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