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传染病学,特定地点的特征和癌瘤的生存率:基于SEER数据库的回顾性研究

Lian-Sha Tang¹, Yu-Wen Zhou², Jia-Ling Wang¹

¹West China Hospital of Sichuan University, Chengdu, China.

|December 15, 2023

概括

癌瘤 (CS) 是一种罕见的癌症,预后不佳. 这项研究发现,CS在各个地点都有独特的特征,攻击性行为在所有地点都很普遍.

科学领域:

在瘤学瘤学.
癌症流行病学癌症流行病学
病理学病理学病理学

背景情况:

癌瘤 (CS) 是一种罕见的,积极的双相恶性瘤,预后不佳.
了解它的流行病学和特定地点的特征对于改善患者的治疗结果至关重要.

研究的目的:

探索原发性瘤 (CS) 的流行病学,特定地点的特征和生存结果.
分析CS发病率的趋势,并确定影响生存的因素.

主要方法:

对监测,流行病学和最终结果 (SEER) 数据库 (1975-2018) 的回顾性分析.
识别了5042个初级CS病例,重点是前五个解剖部位:子宫,双附体,肺,膀和乳房.
根据人口统计和阶段估计发病率,使用结点回归分析趋势分析,以及癌症特异性生存率 (CSS) 和初始治疗的总结.

主要成果:

子宫和双附体占CS病例的近80%. 老年人和黑人人口的年龄调整发病率最高.
从1989年至2018年观察到的远程转移率的增加. 肺和膀CS发生在男性中更频繁,并且发生在区域阶段.
肺部CS的CSS最差 (中位数9.92个月),放射治疗可能没有生存益处. 在每个部位,CS与常见的组织学类型相比,表现出更短的存活期.

结论:

癌瘤表现出明显的临床特征和基于主要瘤位置的显著预后变化.
CS的攻击性是所有主要部位的一致的特征.
进一步研究特定地点的管理策略是有必要的,以改善这种罕见恶性瘤的结果.

关键词:

流行病学流行病学因子分析,统计学分析,统计学分析.预后预后预后

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