相关实验视频

Updated: Jul 8, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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免疫反应3'UTR替代多基化定量特征位点有助于人类复杂特征和疾病的变化

Lei Li1, Xuelian Ma2, Ya Cui3

  • 1Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen, 518055, China. lei.li@szbl.ac.cn.

Nature communications
|December 15, 2023
PubMed
概括

这项研究绘制了人体免疫细胞中免疫替代多基化 (APA) 定量特征位点 (3'aQTLs) 的地图. 这些3'aQTLs将遗传变异与复杂的特征联系起来,其中许多对免疫刺激做出反应,揭示了疾病调节机制.

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