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患有自身免疫性甲状腺疾病的妇女的早期生活压力
Alessia Corso1, Hermann Engel2, Fabienne Müller1
1Institute of Psychology, Clinical Psychology and Psychotherapy, University of Zurich, Binzmuehlestrasse 14, Box 26, 8050, Zurich, Switzerland.
早期的情感忽视和虐待可能会增加患自身免疫性甲状腺疾病 (AITD) 的风险. 这项研究表明,这些因素可能是AITD发展的潜在风险因素.
科学领域:
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
- 精神病学是一个精神病学.
背景情况:
- 自身免疫性甲状腺疾病 (AITD) 很常见,但其原因尚未完全理解.
- 众所周知,生命早期的压力会长期影响免疫系统.
- 早期生活压力和AITD之间的联系以前没有被调查过.
研究的目的:
- 为了检查与对照组相比,AITD患者是否报告了更高的早期生活压力率.
- 确定与AITD相关的特定类型的早期生活压力.
主要方法:
- 一项涉及208名女性的病例控制研究.
- 78名患者患有哈西莫托甲状腺炎,格雷夫斯病或未指定的AITD.
- 130个年龄和BMI匹配的健康对照.
- 童年创伤问卷被用来评估生命早期的压力.
主要成果:
- 在性虐待,身体虐待或身体疏忽率方面,AITD患者和对照组没有差异.
- 患有AITD的患者报告了明显更高的情绪疏忽率 (29.7%与19.5%) 和情绪虐待率 (41.3%与32%).
结论:
- 在生命早期的情感忽视和虐待是发展AITD的潜在风险因素.
- 需要进一步的研究来证实这些发现,并探索预防性干预措施.
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