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神经元特异性TNFAIP1消去减轻了通过向SNAP25对K48相关的全方位化来缓解术后认知功能障碍

Wei Wang1, Wenwei Gao2, Ping Gong1,3

  • 1Department of Anesthesiology, Renmin Hospital of Wuhan University, No.238 Jiefang Road, Wuhan, 430060, China.

Cell communication and signaling : CCS
|December 15, 2023
PubMed
概括

瘤亡因子α诱导蛋白1 (TNFAIP1) 通过降解SNAP25促进术后认知功能障碍 (POCD). 抑制TNFAIP1通过稳定SNAP25来保护POCD,增强线粒细胞和减少热亡.

关键词:
线粒细胞衰变 - - 线粒细胞衰变 (mitophagy) 是一种手术后的认知功能障碍热灭菌的发生.在SNAP25中使用SNAP.在TNFAIP1中.在Ubiquitination中使用.

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