在接种疫苗的医疗保健工作者中,COVID-19后肺功能评估
Lorenzo Ippoliti1, Luca Coppeta2, Giuseppina Somma2
1Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, 00133, Italy. ippoliti.lo@libero.it.
Journal of occupational medicine and toxicology (London, England)
|December 15, 2023
概括
虽然COVID-19感染对医护人员的肺功能产生了负面影响,但疫苗接种显著地保护了这些呼吸系统的下降,特别是强迫生命能力 (FVC). 这凸显了疫苗接种对高压工人的重要性.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- COVID-19可能会导致持续的症状,如疲劳和胸痛,肺部损伤是严重结果的关键因素.
- COVID-19对呼吸功能的长期影响,特别是在轻度病例中,仍然不确定.
- 疫苗对严重的COVID-19是有效的,但它对轻度感染的呼吸功能的影响需要进一步调查.
研究的目的:
- 分析2020-2022年期间COVID-19感染后的医疗保健工作者 (HCW) 肺功能变化.
- 为了比较HCWs的前和后流行性螺旋测试结果.
- 评估疫苗接种状态对SARS-CoV-2感染后呼吸功能的影响.
主要方法:
- 对321台高温电机的螺旋计数据进行了回顾性分析.
- 在COVID-19感染之前和之后的肺功能参数 (FVC,FEV1,FEV1/FVC,PEF) 的比较.
- 线性回归分析,以评估疫苗对呼吸系统参数的保护作用.
主要成果:
- 在流行后,除了FEV1/FVC比率外,螺旋计参数的显著下降也被观察到.
- 与非感染者相比,受感染者在2020年和2021年显著减少了强迫生命能力 (FVC).
- 感染前的疫苗接种与FVC的显着较低的下降有关.
结论:
- 2020-2021年亚临床SARS-CoV-2感染对呼吸系统参数 (FVC,FEV1) 有不利影响.
- 接种COVID-19疫苗证明了对这些呼吸系统下降的保护作用,特别是对于FVC.
- 疫苗接种卫生保健工作者对于减轻COVID-19的长期呼吸系统后果至关重要.
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