末期病患者的深部空间感染:患病率和死亡率
Lillian Acree1, Tyler Day2, Michael W Groves3
1Department of Medicine Augusta University, Augusta, GA, USA.
概括
深部空间感染 (DNSI) 在末期病 (ESRD) 患者中更常见,并显著增加死亡风险. 早期检测和预防措施,如良好的口腔卫生,对于这个脆弱的人群至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 深部空间感染 (DNSI) 是严重的,通常与免疫系统受损有关.
- 脏疾病引起的尿血会损害免疫力,但脏病患者的DNSI研究不足.
研究的目的:
- 为了确定DNSI在美国末期病 (ESRD) 人群中的患病率.
- 调查DNSI与ESRD患者死亡风险之间的关联.
主要方法:
- 使用美国脏数据系统 (2005-2019) 进行的回顾性队列研究.
- 包括705,891名 (18-100岁) 开始透析的患者.
- 使用ICD-9/10代码识别了DNSI和并发症.
主要成果:
- 2.2%的ESRD患者被诊断为DNSI.
- DNSI的危险因素包括女性性别,黑人种族,非AVF接触,自身免疫性疾病,慢性桃体炎,CCI诊断,烟草和酒精使用.
- DNSI是死亡率的独立预测指标,除了年龄较大,非AVF访问,CCI诊断,烟草和酒精使用.
结论:
- 在ESRD人群中,DNSI具有显著的死亡风险.
- 医疗保健提供者应促进口腔卫生和戒烟.
- 密切监测患者对于减轻DNSIESD患者的不良结果至关重要.
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