血管内治疗后多血管封闭性中风患者的结局
Natalie E LeCouffe1, Kilian M Treurniet2,3, Manon Kappelhof2
1Amsterdam UMC, Amsterdam Neuroscience, Department of Neurology, University of Amsterdam, Amsterdam, The Netherlands.
European stroke journal
|December 16, 2023
概括
在接受内血管治疗 (EVT) 的大血管闭塞中风患者中,多血管闭塞 (MVO) 是罕见的. 然而,MVO与EVT后更糟糕的功能结果和增加的死亡率有关.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 脑卒中医学 脑卒中医学
背景情况:
- 大血管封闭 (LVO) 中的多血管封闭 (MVO) 在接受内血管治疗 (EVT) 的中风患者中尚未得到充分了解.
- 了解MVO影响对于优化EVT结果至关重要.
研究的目的:
- 调查MVO在LVO中风患者治疗EVT的功能结果和死亡率的流行率和影响.
- 为了比较MVO和没有MVO的患者之间的结果.
主要方法:
- 对接受EVT的LVO中风患者进行前性观察研究 (MR CLEAN注册表).
- 在基线CTA上,MVO定义为前循环动脉 (MCA,ICA,ACA,PCA) 的并发性闭塞.
- 10:1倾向性得分匹配用于比较MVO和非MVO组之间的结果.
主要成果:
- MVO发生在2.4%的患者 (71/2946),最常见的是涉及ACA.
- 在匹配之前,MVO患者呈现出较高的NIHSS得分和较差的附带状态.
- 在匹配后,MVO与90天的功能结果明显差 (中位数mRS 5vs3) 和较高的死亡率 (46%vs27%) 相关.
结论:
- 在接受EVT的LVO中风患者中,MVO是一种不常见的发现.
- 在EVT之后,MVO独立地与功能性结果差以及死亡率增加有关.
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